Is the product safe for health?

Yes. My son used from 2 month old till turned a year old.

Is there a refill box for reguline? We can only seem to find the standard and the premade options.

No they do not make the refill box for it.

How long can this product be used?

There is an expiration date on the container which was dated a year out. So no need to use it right away

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Enfamil Reguline Baby Formula, Designed for Soft, Comfortable Stools, with Omega-3 DHA & Probiotics for Immune Support, Reusable Powder Tub, 19.5 Oz

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