---
product_id: 34451799
title: "Tylenol Cold + Flu Severe Daytime + Nighttime Cold Medicine Caplets Combo Pack for Multi-Symptom, Cough, Sore Throat, Headache, Nasal Congestion Relief, Acetaminophen, Pain Reliever, 24 Count"
brand: "tylenol"
price: "MX$443"
currency: MXN
in_stock: true
category: "Tylenol"
url: https://www.desertcart.mx/products/34451799-tylenol-cold-flu-severe-daytime-nighttime-cold-medicine-caplets-combo
store_origin: MX
region: Mexico
---

# Day (16) + Night (8) formula split 24 caplets combo pack 325 mg acetaminophen per caplet Tylenol Cold + Flu Severe Daytime + Nighttime Cold Medicine Caplets Combo Pack for Multi-Symptom, Cough, Sore Throat, Headache, Nasal Congestion Relief, Acetaminophen, Pain Reliever, 24 Count

**Brand:** tylenol
**Price:** MX$443
**Availability:** ✅ In Stock

## Summary

> 💥 Conquer cold & flu symptoms day and night — because downtime is not an option!

## Quick Answers

- **What is this?** Tylenol Cold + Flu Severe Daytime + Nighttime Cold Medicine Caplets Combo Pack for Multi-Symptom, Cough, Sore Throat, Headache, Nasal Congestion Relief, Acetaminophen, Pain Reliever, 24 Count by tylenol
- **How much does it cost?** MX$443 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.mx](https://www.desertcart.mx/products/34451799-tylenol-cold-flu-severe-daytime-nighttime-cold-medicine-caplets-combo)

## Best For

- tylenol enthusiasts

## Why This Product

- Trusted tylenol brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **All-Day Multi-Symptom Relief:** Target headaches, cough, congestion & more with tailored daytime and nighttime formulas.
- • **Powerful Pain & Fever Control:** Each caplet delivers 325 mg acetaminophen for fast, effective fever and pain reduction.
- • **Nasal & Chest Congestion Buster:** Phenylephrine HCl and guaifenesin work synergistically to clear nasal passages and loosen mucus.
- • **Nighttime Antihistamine Support:** Chlorpheniramine maleate in night caplets soothes sneezing and sinus pressure for restful sleep.
- • **Trusted Brand with Proven Results:** Tylenol, backed by 10,000+ 4.8-star reviews, ranks top in cold & flu relief categories.

## Overview

Tylenol Cold + Flu Severe Day/Night Caplets Combo Pack offers 24 caplets (16 daytime, 8 nighttime) formulated to relieve multiple cold and flu symptoms including headache, cough, nasal and chest congestion, fever, and sinus pressure. Each caplet contains 325 mg acetaminophen for pain and fever relief, plus targeted ingredients like phenylephrine, guaifenesin, dextromethorphan, and chlorpheniramine to ensure comprehensive symptom control around the clock.

## Description

Tylenol Cold + Flu Severe Day/Night Caplets provide temporary relief from cold and flu relief symptoms. The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. The Nighttime caplets help relieve runny nose and sneezing along with other symptoms such as headache, cough, sore throat, nasal congestion, sinus congestion and pressure. Both multi?symptom cold medicine formulas also temporarily reduce fever, providing effective relief when you need it. This convenient combo pack contains 24 caplets with 16 Daytime caplets and 8 Nighttime caplets. Each medicine caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant. The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus), while the Nighttime caplets contain chlorpheniramine maleate 2 mg, an antihistamine.? *Based on a survey of doctors (IQVIA 2025)

## Features

- 24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. Combo pack includes 16 Daytime and 8 Nighttime caplets for relief when you need it
- The Daytime relief caplets are formulated to reduce fever, loosen phlegm and relieve headache, body aches, cough, sore throat, nasal congestion and chest congestion
- The Nighttime relief caplets help reduce fever and relieve runny nose, sneezing, headache, cough, sore throat, nasal congestion, sinus congestion, and pressure
- Each cold & flu caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant
- The Daytime caplets also contain guaifenesin 200 mg, an expectorant to help loosen phlegm (mucus) to make coughs more productive. The Nighttime caplets also contain 2 mg of chlorpheniramine maleate, an antihistamine

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B01HI7WQRW |
| Active Ingredients | Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl |
| Additional Features | Each caplet contains 325 mg of acetaminophen, a pain reliever and fever reducer; 5 mg of phenylephrine HCl, a nasal decongestant; and 10 mg of dextromethorphan HBr, a cough suppressant |
| Age Range Description | Adult |
| Best Sellers Rank | #3,664 in Health & Household ( See Top 100 in Health & Household ) #18 in Sinus Medicine #37 in Cough & Cold Medicine #441 in Sales & Deals |
| Brand | Tylenol |
| Brand Name | Tylenol |
| Container Type | Box |
| Customer Reviews | 4.8 out of 5 stars 10,689 Reviews |
| Flavor | Day & Night - Cold + Flu |
| Global Trade Identification Number | 00300450550248 |
| Item Dimensions | 4.52 x 0.78 x 2.95 inches |
| Item Form | Caplets |
| Item Weight | 1.28 ounces |
| Item dimensions L x W x H | 4.52 x 0.78 x 2.95 inches |
| Manufacturer | Kenvue |
| Manufacturer Part Number | 30045055024 |
| Model Name | Tylenol Cold & Flu Medicine |
| Model Number | 30045055024 |
| Net Content Count | 24 Count |
| Number of Items | 1 |
| Package Type Name | Blister |
| Product Benefits | Pain Relief, Fever Control, Nasal Relief, Chest Congestion Relief, Cough Relief, Headache Relief, Sinus Control, Cold and Flu Control Product Benefits Pain Relief, Fever Control, Nasal Relief, Chest Congestion Relief, Cough Relief, Headache Relief, Sinus Control, Cold and Flu Control See more |
| Specific Uses For Product | Cold, Flu, Fever, Cough , Nasal Congestion, Sore Throat, Runny Nose, Headache, Chest Congestion, Sneezing, Sinus Pressure, Cough Specific Uses For Product Cold, Flu, Fever, Cough , Nasal Congestion, Sore Throat, Runny Nose, Headache, Chest Congestion, Sneezing, Sinus Pressure, Cough See more |
| Target Audience | Unisex-Adults |
| Target Use Body Part | Body |
| UPC | 300450550248 |
| Unit Count | 24.0 Count |

## Product Details

- **Brand:** Tylenol
- **Item Weight:** 1.28 ounces
- **Item dimensions L x W x H:** 4.52 x 0.78 x 2.95 inches

## Images

![Tylenol Cold + Flu Severe Daytime + Nighttime Cold Medicine Caplets Combo Pack for Multi-Symptom, Cough, Sore Throat, Headache, Nasal Congestion Relief, Acetaminophen, Pain Reliever, 24 Count - Image 1](https://m.media-amazon.com/images/I/81T0pqFnZ8L.jpg)

## Questions & Answers

**Q: What is TYLENOL?**
A: Acetaminophen is an active ingredient in all TYLENOL products and in more than 600 other over-the-counter (OTC) and prescription medicines. Do not take more than one medicine containing acetaminophen at the same time.

**Q: How much TYLENOL can I take?**
A: TYLENOL is safe and effective when used as directed. The safety of TYLENOL at recommended doses has been established through 50 years of use and scientific investigation. Do not exceed the recommended dosage as it may cause liver damage.

**Q: How does TYLENOL work?**
A: TYLENOL contains the active ingredient acetaminophen, which is a pain reliever and fever reducer. It works by elevating the body's overall pain threshold so you feel less pain, and lowers your fever by helping your body eliminate excess heat.

## Frequently Bought Together

- Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
- VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
- Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct

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**Shop now:** [https://www.desertcart.mx/products/34451799-tylenol-cold-flu-severe-daytime-nighttime-cold-medicine-caplets-combo](https://www.desertcart.mx/products/34451799-tylenol-cold-flu-severe-daytime-nighttime-cold-medicine-caplets-combo)

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*Product available on Desertcart Mexico*
*Store origin: MX*
*Last updated: 2026-07-22*