--- product_id: 4856825 title: "FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box)" brand: "frontline" price: "MX$3530" currency: MXN in_stock: true reviews_count: 9 category: "Frontline" url: https://www.desertcart.mx/products/4856825-frontline-plus-for-dogs-flea-and-tick-treatment-extra-large store_origin: MX region: Mexico --- # 30-day protection Waterproof formula Kills fleas, eggs & ticks FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) **Brand:** frontline **Price:** MX$3530 **Availability:** ✅ In Stock ## Summary > 🛡️ Keep your best friend itch-free and unstoppable all month long! ## Quick Answers - **What is this?** FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) by frontline - **How much does it cost?** MX$3530 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.mx](https://www.desertcart.mx/products/4856825-frontline-plus-for-dogs-flea-and-tick-treatment-extra-large) ## Best For - frontline enthusiasts ## Why This Product - Trusted frontline brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Month-Long Defense:** One monthly dose shields your dog for a full 30 days—no gaps, no worries. - • **Waterproof & Active:** Water-resistant formula keeps working even after baths or rainy walks. - • **Trusted for 20+ Years:** Veteran pet owners rely on FRONTLINE Plus for proven, consistent protection. - • **Complete Flea Lifecycle Kill:** Targets adult fleas, eggs, larvae, and ticks to break infestations fast. - • **Easy, Stress-Free Application:** Single spot application between shoulder blades—no mess, no fuss. ## Overview FRONTLINE Plus for Dogs (Extra Large, 89-132 lbs.) is a vet-trusted, waterproof topical treatment that kills fleas, flea eggs, larvae, chewing lice, and ticks—including those that transmit Lyme disease. With a single monthly dose, it provides continuous protection by depositing active ingredients in the skin’s sebaceous glands, ensuring fast-acting and long-lasting defense. Suitable for dogs as young as 8 weeks and weighing 5 pounds or more, this 6-dose pack offers hassle-free, proven flea and tick control trusted by pet owners for over two decades. ## Description Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention. Review: Works great and long lasting - Works great long lasting. The only brand that doesn't bother my babies sensitive skin. Will continue to buy the price is great for 3!! No lingering odor either and you don't have to put it down the entire length of their back. Review: Still works in my part of the state - Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away... ## Features - Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease - Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control - Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days - FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products - Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations - Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0002J1FPI | | Active Ingredients | fipronil and (S)-methoprene | | Age Range Description | All Life Stages | | Allergen Information | Abalone Free | | Best Sellers Rank | #894 in Pet Supplies ( See Top 100 in Pet Supplies ) #10 in Dog Flea Drops | | Brand | Frontline | | Brand Name | Frontline | | Customer Reviews | 4.4 out of 5 stars 15,306 Reviews | | Dog Breed Size | Giant | | Included Components | Package includes 6 applicators | | Item Form | Liquid | | Item Type Name | Topical Red box | | Item Volume | 24 Milliliters | | Item Weight | 2.4 ounces | | Manufacturer | Boehringer Ingelheim Animal Health | | Manufacturer Part Number | 292919 | | Model Number | 72220 | | Scent | Unscented | | Scent Name | Unscented | | Target Species | Dog | | UPC | 877157002139 062701655330 350604288305 | | Unit Count | 6 Count | | Volume | 24 Milliliters | | Warranty Description | No Warranty | ## Product Details - **Active Ingredients:** fipronil and (S)-methoprene - **Age Range (Description):** All Life Stages - **Allergen Information:** Abalone Free - **Brand:** Frontline - **Dog Breed Size:** Giant - **Item Form:** Liquid - **Item Volume:** 24 Milliliters - **Item Weight:** 0.15 Pounds - **Scent:** Unscented - **UPC:** 877157002139 062701655330 350604288305 ## Images ![FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) - Image 1](https://m.media-amazon.com/images/I/71+BuWcmHeL.jpg) ![FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) - Image 2](https://m.media-amazon.com/images/I/81HWNyMk9sL.jpg) ![FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) - Image 3](https://m.media-amazon.com/images/I/814CcTxB26L.jpg) ![FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) - Image 4](https://m.media-amazon.com/images/I/814n+7Kn+kL.jpg) ![FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) - Image 5](https://m.media-amazon.com/images/I/81dlsY2VC9L.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: is this product from famous shamus the fontline plus made and approved for use in the usa** A: The Frontline I purchased online is called Frontline Combo. The box has on it...6 pipettes of 2.68 ml...For dogs 20-40 kgMA/VPA Merial Health Limited, PO Box 327, Harlow, Essex, CM19 5TG, United Kingdom Manufacturer: Merial - Toulouse - France. I put the product on him and everything is fine. **Q: I've been using Frontline Plus for years, but lately it seems to be not as effective as it used to be. Has anyone noticed the same results ?** A: Yes! After trying multiple flea & tick medication, my dog wasn’t getting any better...took her to the vet & she stated that the over the counter flea & tick medication isn’t effective since it’s been on the market for some time, the fleas have evolved & aren’t responding to the meds. Plus she said this season has been the worst so that doesn’t help either!!! Take them to the vet, my dog now is flea/tick free **Q: Can I give her a bath** A: "It is OK to bathe your pet before using FRONTLINE, but the coat should be completely dry prior to application. In the 48 hours immediately after treatment, do not bathe, shampoo or let your dog go swimming." (FRONTLINE webste) This medication works systemically after being absorbed through the skin. Insufficient dosing will lead to product failure. **Q: Can this work with a 120 pounds dog?** A: you have to buy the frontline plus for 80-120 lbs dogs. yes then that woulkd work for preventing ticks , fleas from infecting your dog. ask your vet if any doubts. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Works great and long lasting *by V***8 on May 23, 2026* Works great long lasting. The only brand that doesn't bother my babies sensitive skin. Will continue to buy the price is great for 3!! No lingering odor either and you don't have to put it down the entire length of their back. ### ⭐⭐⭐⭐⭐ Still works in my part of the state *by S***H on September 23, 2024* Easy to apply if you can make a part in your dog's hair. I always get it on my hands and wash it off as soon as I am done with the dogs. Never a problem on my skin due to this timeliness I guess. Kills the ticks who settle down to bite and still works on fleas for me. Ten miles down the road, however, it does not work anymore. Life finds away... ### ⭐⭐⭐⭐⭐ Outstanding product value *by S***S on May 7, 2026* Outstanding product, exactly as described and needed. ## Frequently Bought Together - FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 6 Doses (Red Box) - Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments - Frontline Plus for Dogs Medium Dog (23-44 pounds) Flea and Tick Treatment, 6 Doses --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.mx/products/4856825-frontline-plus-for-dogs-flea-and-tick-treatment-extra-large](https://www.desertcart.mx/products/4856825-frontline-plus-for-dogs-flea-and-tick-treatment-extra-large) --- *Product available on Desertcart Mexico* *Store origin: MX* *Last updated: 2026-06-01*