---
product_id: 539193876
title: "Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version"
brand: "apagard"
price: "$2608"
currency: MXN
in_stock: true
reviews_count: 5
category: "Apagard"
url: https://www.desertcart.mx/products/539193876-premio-toothpaste-105g-3-7-oz-nano-hydroxyapatite-high-blending
store_origin: MX
region: Mexico
---

# Brightens teeth naturally without harsh chemicals Nano-hydroxyapatite remineralizes enamel Authentic Japanese dental innovation Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version

**Brand:** apagard
**Price:** $2608
**Availability:** ✅ In Stock

## Summary

> 🦷 Brighten your smile the Japanese way — science meets sophistication!

## Quick Answers

- **What is this?** Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version by apagard
- **How much does it cost?** $2608 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.mx](https://www.desertcart.mx/products/539193876-premio-toothpaste-105g-3-7-oz-nano-hydroxyapatite-high-blending)

## Best For

- apagard enthusiasts

## Why This Product

- Trusted apagard brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Trusted Japanese Formula:** Backed by decades of innovation from Sangi Co., Ltd, Japan’s oral care pioneer.
- • **Family-Friendly Volume & Use:** Generous 105g tubes in a convenient 2-pack, perfect for daily use by all ages.
- • **Gentle Yet Effective Whitening:** Enhances natural whiteness and controls stains without sensitivity or abrasive agents.
- • **All-Day Freshness & Breath Care:** Balances breath care with stain control for confident social moments.
- • **Enamel-Boosting Nano Technology:** Harnesses nano-mHAP, the same mineral as your teeth, for deep remineralization and plaque removal.

## Overview

Apagard Premio Toothpaste features Japan’s original nano-hydroxyapatite formula that remineralizes enamel, whitens teeth naturally, and controls plaque and stains. This 2-pack of 105g tubes offers a trusted, gentle, and effective oral care solution designed for daily use by adults seeking a radiant, healthy smile backed by decades of Japanese dental innovation.

## Description

Ingredients (INCI name): AQUA, DICALCIUM PHOSPHATE, GLYCERIN, HYDROXYAPATITE, SILICA, PEG-8, SODIUM LAURYL SULFATE, CELLULOSE GUM, AROMA, TRIMAGNESIUM PHOSPHATE, HYDROLYZED CONCHIOLIN PROTEIN, SODIUM SACCHARIN, GLYCYRRHETINIC ACID, CETYLPYRIDINIUM CHLORIDE, LAURYL IETHYLENEDIAMINOGLYCINE HCL

Review: I read an article several years ago about hydroxyapatite toothpaste, and gave it a try. I will never go back, and have been so pleased with the appearance and feel of my teeth in my mouth. I have tried many different brands during this time, and this brand really stood out to me, with its pleasant taste, excellent cleaning, and great mouth feel. In all fairness, there are many other great brands available, which are also very good. Since finding this new type of toothpaste, I have to question why it is not available mainstream in the US, and advertised. My dentist asked me if I was using a teeth whitening product, and didn’t seem very welcoming, when I shared what I was using. This product, cleans, whitens, and works to prevent teeth sensitivity. Excellent product.
Review: 良い商品です。

## Features

- APAGARD, Japan's leading toothpaste series for naturally beautiful teeth, is now available in the US. Discover the secret of naturally beautiful teeth from Japan. Contains Sangi's original nano-hydroxyaptite (nano-mHAP), almost the same substance as the hydroxyapatite that our teeth are made of, first synthesized in the 1970s by Sangi Co., Ltd
- APAGARD cleans the teeth and helps remove plaque with regular brushing.
- APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package, ideal for family use.
- For the best effect from nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/day is recommended) (3) Rinse lightly and spit out after brushing, so nano-mHAP remaining will enrich your saliva and continue its work.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0C379SKGN |
| ASIN  | B0C379SKGN |
| Age Range Description | Adult |
| Best Sellers Rank | #60,110 in Health ( See Top 100 in Health ) #1,643 in Toothpaste |
| Brand | APAGARD |
| Customer Reviews | 4.5 4.5 out of 5 stars (1,231) |
| Customer reviews | 4.5 4.5 out of 5 stars (1,231) |
| Date First Available | 20 June 2023 |
| Format | Paste |
| Item model number  | 4987643122183 |
| Manufacturer  | SANGI Co., Ltd. |
| Package Dimensions  | 17.8 x 4.6 x 3.6 cm; 0.14 g |
| Units | 218.84 Milliliters |

## Product Details

- **Age range (description):** Adult
- **Brand:** APAGARD
- **Flavour:** Mint
- **Item form:** Paste
- **Material type free:** Fluoride Free

## Images

![Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 2) 2-Pack 2023 Version - Image 1](https://m.media-amazon.com/images/I/61eDwvzPDGL.jpg)

## Questions & Answers

**Q: Complete list of ingredients?**
A: Google "Premio Apagard ingredients", it's in English on several websites. It's also in Japanese and English on the product box, just not on the tube itself.

**Q: Still flouride free?**
A: Fluoride is not listed as an ingredient on the outside of the box that the tube is shipped in. An additional label in English is pasted over the Japanese, I suppose for when the product is shipped to an English-speaking country.

**Q: Does this toothpaste have an expiration in storage?**
A: The shelf life of Apagard Premio toothpaste is two years.

**Q: What is the percentage of Nano Hydroxyapatite? And what is the flavor?**
A: Apagard uses 10% and 15%, depending on the toothpaste. But that's not total % of the toothpaste in the tube. That suspension is added to the toothpaste. Boka uses a 15.5% suspension, and the total amount is 2% of the toothpaste.  The flavor of the toothpaste is a very light mint.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by W***S on 7 September 2025*

I read an article several years ago about hydroxyapatite toothpaste, and gave it a try. I will never go back, and have been so pleased with the appearance and feel of my teeth in my mouth. I have tried many different brands during this time, and this brand really stood out to me, with its pleasant taste, excellent cleaning, and great mouth feel. In all fairness, there are many other great brands available, which are also very good. Since finding this new type of toothpaste, I have to question why it is not available mainstream in the US, and advertised. My dentist asked me if I was using a teeth whitening product, and didn’t seem very welcoming, when I shared what I was using. This product, cleans, whitens, and works to prevent teeth sensitivity. Excellent product.

### ⭐⭐⭐⭐⭐ Review
*by 岡***元 on 21 January 2026*

良い商品です。

### ⭐⭐⭐⭐ Review
*by 龍***虎 on 9 December 2025*

歯磨きの時にあまり鏡を見る習慣がなく、久々に鏡を見たら茶渋で凄いことになっていた。 もちろん歯磨きはシッカリしていたのですが。 歯科医でホワイトニングを頼もうか悩んでいた時に、これを見付けて購入。 茶渋、そんなに着色していなかったのか？ 歯磨き2日目で綺麗になりました。 液体ハミガキとこちらと両方使っています。

## Frequently Bought Together

- APAGARD® PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2
- Boka Fluoride Free Toothpaste Nano Hydroxyapatite, Helps Remineralize, Appropriate for Sensitive Teeth, Whitening - for Adult, Kids Oral Care - Refresh Mint Flavor, 4 Fl Oz 1Pk
- Apagard Tooth Polish Royal 135g toothpaste, Direct from Japan

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---

*Product available on Desertcart Mexico*
*Store origin: MX*
*Last updated: 2026-03-06*